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Oxygen transfer rates

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Lowwell plate covers and clamps

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Growth profiler 1152

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Literature/conferences

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Recent talks on growth in microtiter plates.
 
  • 1-5 August, 2010, SIM, Annual Meeting and Exhibition, talk Wouter Duetz entitled: "Cultivation in various types of microtiter plates, and quantification of cell mass using flatbed scanning and image analysis software"
 
  • SGM meeting Edinburgh, 7-11 September 2009, "Cultivation and biotransformation in microtiter plates", by Wouter Duetz (part of a session organized by Krist Gerneay, called "Cultivating and sensing microbes in micro-scale devices" , for a complete programme of this session, see: www.sgm.ac.uk/meetings/MTGPAGES/hw0908.cfm
 
  • RAFT meeting, San Diego, 8-11 November 2009 "Cultivation in microtiter plates, quantification of biomass using flatbed scanning technology" by Wouter Duetz". This talk is part of a session called "New fermentation Technology" organized by Jeff Keating and Wouter Duetz. For a complete programme, see www.simhq.org/meetings/meetings.aspx
 
 
Relevant literature:
 
 
Recent review articles & patent applications:
 
  • Duetz, W.A., Chase, M., Bills, G. (2010)  Miniaturization of Fermentations. Chapter 8, ASM Manual of Industrial Microbiology and Biotechnology, R. H. Baltz, J. E. Davies, A. L. Demain (eds)
 
  • Duetz, W.A. November 2008. An apparatus and a method for investigation of microtiter plates subjected to orbital shaking. Patent 86185NL00 (note: this patent application concerns the application of flatbed scanning technology for the quantification of biomass in microtiter plate wells during a short interruption in their orbital shaking)
 
  • Duetz, W.A. (2007) Microtiter plates as mini-bioreactors: miniaturization of fermentation methods, TRENDS in Microbiology 15 (10): 470-475
 
  • Duetz, W.A., Kuhner M., Lohser R. (2006) Microbial and cell growth in microtiter plates, GENETIC ENGINEERING NEWS 26 (11): 44-46 JUN 1 2006
 
 
Key research article:
  • Duetz, W.A., Rüedi, L., Hermann, R. O'Connor, K, Büchs, J., and Witholt, B. (2000). Methods for intense aeration, growth, storage, and replication of bacterial strains in microtiter plates. Applied and Environmental Microbiology 66:2641-2646 (pdf-file, 146kb)  
 
Other articles:
 
  • Minas, W., Bailey, J.E., Duetz, W.A. (2000). Streptomycetes in microcultures: growth, production of secondary metabolites, and storage and retrieval in the 96-well format. Antonie van Leeuwenhoek, 78 (3-4): 297-305 (pdf-file, 213 kb)
 
  • Clerval, R., Kühner, M., Li, Z., Minas, W., Fjällman, A., Witholt, B. and Duetz, W.A. (2000). The come-back of high-throughput screening of wild-type microbial strains through the use of miniaturised growth systems and LC-MS. Bioworld 6: 24-26
 
  • Duetz, W.A. and Witholt, B. (2001). Effectiveness of orbital shaking for the aeration of suspended bacterial cultures in square deepwell microtiter plates. Biochemical Engineering Journal, 7: 113-115 (pdf-file, 94 kb)
 
  • Duetz, W.A., Minas, W., Kuhner, M., Clerval, R., Fjallman, A.H.M., Witholt, B. (2001). Miniaturized microbial growth systems in screening. Bioworld 2: 8-10 (pdf-file, 2252 kb)
 
  • Duetz, WA, Witholt, B. (2004). Oxygen transfer by orbital shaking of square vessels and deepwell microtiter plates of various dimensions. Biochemical Engineering Journal 17: 181-185 (pdf-file, 75 kb)